Recent advances in the chemistry of Trichloromethyl chloroformate and bis-(trichloromethyl) carbonate

摘要

Trichloromethyl chloroformate (TCF,diphosgene,1) and bis-(trichloromethyl) carbonate (BTC,triphosgene,2),two important substitutes for phosgene,have emerged as versatile synthetic auxiliaries for the synthesis of important classes of organic compounds.Recently,for example,a large number of compounds with high biological activities have been synthesized by use of TCF and BTC.The present review presents a summary on the recent development of TCF and BTC.