During the 1990s a lot of technology seemed to emerge in parallel, including ultrahigh-throughput automation and cell-based assays in the HCS area. People may have been fairly open early on to the idea of integrating high content imaging into the area of high-throughput screening, but after a period of time there was less of a drive to integrate high content with other technologies such as high-throughput automation. The assays that are commonly used now have not changed much in the past 5-6 years. They might be slightly higher throughput, but they have basically plateaued in terms of technology development.
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