NA;The effects of polystyrene cerebral emboli of the order of 60 to 120mgr; in the monkey have been studied by serial conventional angiography lpar;indirect effectsrpar; and photographically enlarged industrial filming lpar;direct effectsrpar;. Findings werecolon; diffuse or locally poor capillary phase, mixed arteriovenous phases, general or locally poor venous phase, arterial dilatation and stasis within vessels over 500mgr; in diameter. A suggestion of leptomeningeal immediate collaterals and definite spasm of small arteries could be seen. The emboli generally could be seen only with photographically enlarged industrial arteriograms. Papaverine hydrochloride caused vasodilatation of arteries less than 300mgr;, with no discernible effects on larger arteries. The poor capillary and venous phases in the embolized animal were improved with papaverine. Tolazoline hydrochloride administered intrahyphen;arterially caused marked vasoconstriction of vessels smaller than 300mgr; and diminution in the capillary and venous phases, and was uniformly associated with mortality of the animal in 30 minutes.
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