机译:活性位点诱导的进化约束遵循可溶性球状酶的折叠极性原理
Univ Cambridge, Dept Chem, Cambridge, England;
Ecole Polytech Fed Lausanne, Lab Biomol Modeling, Lausanne, Switzerland;
protein evolution; fold polarity; structure-constrained evolution; structure-function relationships; protein biophysics; structural biology;