Features and management of poisoning with modern drugs used to treat epilepsy

摘要

Overdosage with anticonvulsant drugs is a serious problem andphysicians should be particularly alert to its occurrence in theepileptic population. The majority of patients develop centralnervous system or cardiovascular symptoms and signs of toxicity.Knowledge of overdosage with the newer anticon- vulsant drugs such aslamotrigine and vigabatrin is limited, and clinicians should beencouraged to report any cases encountered in the literature.Meticulous supportive care is required to achieve A good outcome inanticonvulsant drug poisoning; gastric lavage and activated charcoalshould be given if the patient presents within 1-2 h of the overdose.