Imaging autofluorescence temporal signatures of the human ocular fundus in vivo

摘要

We demonstrate real-time in vivo fundus imaging capabilities of our fluorescence lifetime imaging technology for the first time. This implementation of lifetime imaging uses light emitting diodes to capture full-field images capable of showing direct tissue contrast without executing curve fitting or lifetime calculations. Preliminary results of fundus images are presented, investigating autofluorescence imaging potential of various retina biomarkers for early detection of macular diseases. (C) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)