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>Prekallikrein Activation, C1 Esterase Inhibitor, and Factor XII as Predictors of Adverse Reaction to Contrast MediaA Prospective Study
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Prekallikrein Activation, C1 Esterase Inhibitor, and Factor XII as Predictors of Adverse Reaction to Contrast MediaA Prospective Study
The susceptibility of 152 patients to idiosyncratic reactions resulting from the administration of radiographic contrast media was studied. The rate of activation of plasma prekallikrein was measured in samples taken from these patients before they received contrast agents. Kallikrein inhibitor and factor XII levels were also determined. The tests were of no value in selecting the ten patients who subsequently experienced mild reactions. However, the possibility remains that one or more of the tests may have predictive value for patients who experience moderate or severe reactions.
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机译:研究了 152 名患者对放射造影剂施用引起的特异质反应的易感性。血浆前激肽释放酶的活化率是在这些患者接受造影剂之前采集的样本中测量的。还测定了激肽释放酶抑制剂和因子 XII 水平。这些测试在选择随后出现轻微反应的十名患者时没有价值。然而,一项或多项测试可能对出现中度或重度反应的患者具有预测价值。
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