Allergic reactions to the Australian paralysis tick,Ixodes holocyclus: diagnostic evaluation by skin test and radioimmunoassay

摘要

SummaryAllergic reactions toIxodes holocyclusare well recognized but poorly defined. Tick‐bite reactions in 42 individuals in this study fell into six classes. Skin‐prick tests and radioimmunoassay (RIA) indicated that all systemic hypersensitivity (class 3) and atypical reactions (class 4) were IgE‐mediated. Some 73 of the large local reactions (class 2) and only 12.5 of the small local reactions (class 1) were associated with IgE specific for tick allergens. Subjects who reported heavy exposure to tick‐bite were more likely to have positive RIA values (P<0.05). There was an association between the individual's atopic status and tick allergy (