机译:合成1,2-苯并异噁唑拴系1,2,3-三唑,通过抑制组蛋白脱乙酰酶和诱导p21和微管蛋白乙酰化在急性髓系白血病细胞系中表现出抗癌活性
Univ Mysore, Dept Studies Chem, Mysore 570005, Karnataka, India;
Natl Univ Singapore, Canc Sci Inst Singapore, Genom Oncol Programme, Singapore 117599, Singapore;
Univ Cambridge, Dept Chem, Ctr Mol Sci Informat, Cambridge CB2 1EW, EnglandHokkaido Univ, Frontier Res Ctr Postgenome Sci & Technol, Sapporo, Hokkaido 060, JapanBangalore Univ, Dept Chem, Biol Chem Lab, Bangalore 560001, Karnataka, India;
Histone deacetylase; 1; 2; 3-Triazoles; Histone 3 acetylation; Acute myeloid leukemia;