Drughyphen;induced hypoglycaemia

摘要

Drug-induced hypoglycaemia can occur because of reduced glucose appearance in the blood, or increased glucose disappearance from the blood. The most important causes of the former are:ethanol (especially in children), salicylates in high dosage, and, rarely, dextropropoxyphene. Glucose disappearance can be enhanced by:insulin, insulin-like growth factor-l; and sulphonylureas, pentamidine, quinine and other drugs that cause insulin secretion.Drugs that interact with the sympathetic nervous system can lower blood glucose concentration or impair responses to hypoglycaemia: they include the non-selective beta-adrenoceptor blocking drugs and beta, adrenoceptor stimulants.