Modification of Bone Formation Rate by Growth Hormone, Melanocyte-Stimulating Hormone, and Cortisone in the Normal Rat

摘要

Bone growth and remodelling was studied in rats after injection of growth hormone, melanocyte-stimulating hormone (α-MSH), and cortisone daily for 20 days with tetracycline as intravital marker. An increase of both longitudinal and periosteal growth with growth hormone was found. A decrease of both was found after a high cortisone dose. Lower cortisone doses seem to have stimulated periosteal growth. No effect of α-MSH was foun