Genomic Exploration of the Hemiascomycetous Yeasts: 13. Pichia angusta

摘要

As part of a comparative genomics project on 13 hemiascomycetous yeasts, the Pichia angusta type strain was studied using a partial random sequencing strategy. With coverage of 0.5 genome equivalents, about 2500 novel protein-coding genes were identified, probably corresponding to more than half of the P. angusta protein-coding genes, 6 of which do not have homologs in Saccharomyces cerevisiae . Some of them contain one or two introns, on average three times shorter than those in S. cerevisiae . We also identified 28 tRNA genes, a few retrotransposons similar to Ty5 of S. cerevisiae , solo long terminal repeats, the whole ribosomal DNA cluster, and segments of mitochondrial DNA. The P. angusta sequences were deposited in EMBL under the accession numbers AL430961 to AL436044.