Opacification of the Mediastinal Nodes by the Intrapleural Injection of Two Types of EmulsionsStudy of Their Effect upon the Pleura

摘要

NA;Two types of emulsions of Ethiodol were used for the opacification of the mediastinal nodes. These contrast media were injected intrapleurally, and their effect upon the pleura and lymph nodes was studied. A total of 10 dogs was utilized. Six dogs received Emulsion I, and six received Emulsion II (2 dogs received both emulsions). Each dog had a baseline chest x‐ray, white cell count, and body temperature determination. After the injection of the contrast medium, these examinations were repeated on days 2, 7, and 14. The animals were sacrificed within 2 to 66 days. At that time, careful dissection of the mediastinal nodes was performed. The mediastinal nodes were reexamined by contact x‐ray, and the presence or absence of contrast medium in the dissected nodes was determined; 80—100 of the anterior mediastinal nodes were opacified by both media. The tracheobronchial nodes were usually not well opacified by both emulsions, although Emulsion II was found to be slightly superior. Emulsion II produced moderate‐to‐severe pleural reaction in all cases, while no significant tissue reaction was found with Emulsion I. Our results seem to indicate that Emulsion I is well tolerated in the animal. Although the number of dogs studied is small, we believe that Emulsion I or a similar contrast medium might become a suitable agent for mediastinal lymphography. A larger number of animals should be studied prior to human application.