CAUSES OF HYPERhyphen;CKhyphen;EMIA IN A NEUROLOGICAL DEPARTMENT

摘要

BACKGROUNDThis study examined causes of elevated serum creatine kinase lpar;hyperhyphen;CKhyphen;emiarpar; and its frequencies in a neurological department. Few data are available about this topic. We retrospectively evaluated the medical records of all inpatients with hyperhyphen;CKhyphen;emia greater than 70 Usol;L admitted to our department between October 1995 and October 1998.REVIEW SUMMARYAmong 3,601 patients admitted during this period, 426 lpar;12percnt;rpar; lpar;165 women and 261 men, age 21 to 97 yearsrpar; had hyperhyphen;CKhyphen;emia. The most frequent causes of hyperhyphen;CKhyphen;emia were stroke lpar;21percnt;rpar;, trauma lpar;18percnt;rpar;, idiopathic hyperhyphen;CKhyphen;emia lpar;14percnt;rpar;, and seizures lpar;12percnt;rpar;. In 42 patients, two or three causes for hyperhyphen;CKhyphen;emia were found. Depending on the diagnostic group, mean CK ranged between 129 Usol;L lpar;thyroid dysfunctionrpar; and 882 Usol;L lpar;electrolyte disturbancesrpar;. A total of 72percnt; of patients had hyperhyphen;CKhyphen;emia up to 200 Usol;L, and 96percnt; up to 1,000 Usol;L. Only one patient had CK greater than 5,000 Usol;L. The oldest patients with hyperhyphen;CKhyphen;emia were those with myocardial infarction, and the youngest were those with multiple sclerosis. Hyperhyphen;CKhyphen;emia occurred more frequently in men than in women.CONCLUSIONSHyperhyphen;CKhyphen;emia was found in 12percnt; of the patients admitted to our neurological department. In the majority of the patients, CK elevations were only mild. The most frequent causes of hyperhyphen;CKhyphen;emia were stroke, trauma, and seizures.lpar;THE NEUROLOGIST 6colon;309hyphen;314, 2000rpar;