Crosslinked polyethylene (PE) was developed to reduce volumetric wear in prosthetic joints. Hip simulator studies have shown promising results but there is as yet limited clinical data. We identified three patients with bilateral total hip replacements who received a crosslinked PE liner (Marathon, DePuy, Warsaw, IN, USA) on one side and a conventional PE insert (Enduron, DePuy) on the contralateral side. As an assessment of in vivo PE wear, linear head penetration was measured on standardized radiographs using a validated computer-assisted technique. In all the three cases, a marked reduction of more than 70 in volumetric wear was found in association with Marathon crosslinked PE. These case reports support the efficacy of this type of crosslinked PE in a selected group that allows direct comparison of the two different materials without the influence of patient-related factors such as activity, gender, weight, or others.
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机译：交联聚乙烯 （PE） 旨在减少假肢关节的体积磨损。髋关节模拟器研究已显示出有希望的结果，但临床数据有限。我们确定了三名双侧全髋关节置换术患者，他们一侧接受交联 PE 衬垫（Marathon， DePuy， Warsaw， IN， USA），对侧接受常规 PE 插入物（Enduron、DePuy）。作为体内 PE 磨损的评估，使用经过验证的计算机辅助技术在标准化 X 光片上测量线性头部穿透力。在所有三种情况下，发现与马拉松交联PE相关的体积磨损显着减少了70%以上。这些病例报告支持这种类型的交联 PE 在选定组中的疗效，可以直接比较两种不同的材料，而不受患者相关因素（如活动、性别、体重或其他）的影响。
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