AbstractAryl esterases, present within leaves and fungal spores and on their surfaces, hydrolysed 2‐naphthyl, 4‐nitrophenyl and 4‐(1‐substituted alkyl)‐2, 6‐dinitrophenyl esters at rates which appeared to be determined by the nature of the ester group and by the alkyl substituents in the molecule. No simple relationship was found between partitioning (as measured by Rm values from reverse‐phase t.l.c.) and susceptibility to hydrolysis by esterases. The most readily hydrolysed alkyldinitrophenyl esters are not those derived from parent nitrophenols with the greatest fungitoxicity in vivo or in vitro and the highly active 4‐(1‐cyclobutylalkyl)‐2, 6‐dinitrophenyl crotonates are amongst the least easily hydrolysed. It is suggested that alkyldinitrophenyl esters may have their own mode of action as powdery mildew fungicides which complements, and may even supplant, that resulting from hydrolysis to the parent alkyldinitrophenol. The proposed mechanism is disruption of the fungal cell membrane (as a result of surfactant properties) leading to leakage of esse
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机译:摘要 存在于叶片和真菌孢子内及其表面的芳基酯酶水解了2-萘基、4-硝基苯基和4-(1-取代的烷基)-2,6-二硝基苯酯,其速率似乎取决于酯基的性质和分子中的烷基取代基。在分配(通过反相t.l.c的Rm值测量)和酯酶水解的敏感性之间没有发现简单的关系。最容易水解的烷基二硝基苯酯不是来自母体硝基酚的酸酯,在体内或体外具有最大的真菌毒性,而高活性的4-(1-环丁基烷基)-2,6-二硝基苯基巴豆酸酯是最不容易水解的。有人认为,烷基二硝基苯酯可能具有自己的作用方式,作为白粉病杀菌剂,可以补充甚至取代水解为母体烷基二硝基苯酚产生的作用方式。所提出的机制是真菌细胞膜的破坏(由于表面活性剂性质)导致 esse 泄漏
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