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Emergent Comorbidity in At Risk Children with and without Autism Spectrum Disorder-A Cross-Sectional Study

机译:患有和不患有自闭症谱系障碍的高危儿童的紧急合并症-横断面研究

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摘要

Individuals with autism spectrum disorders (ASD) are noted to be at an increased risk for developing comorbid psychiatric conditions. Little is known about the emergence and etiology of comorbid conditions in ASD. We investigated if this pattern of comorbidity can be detected in those with ASD at an early age. Two-hundred and sixty-nine atypically developing toddlers classified as ASD (n= 109) or non-ASD (n= 160) were studied using the Baby and Infant Screen for aUtlsm Traits-Part 2 {BISCUIT-Part 2). Participants were divided into four age groups: 12-18 months, 19-24 months, 25-31 months, and 32-39 months. A factorial MANOVA was used to assess age and diagnostic group differences on BISCUIT-Part 2 domains. A general trend emerged where toddlers with ASD appeared to have more severe symptoms than atypically developing non-ASD toddlers with there being an increasing trend of comorbid behaviors as age increased. Results and implications are discussed.
机译:自闭症谱系障碍 (ASD) 患者患共病精神疾病的风险增加。对 ASD 合并症的出现和病因知之甚少。我们研究了是否可以在早期ASD患者中检测到这种合并症模式。269 名被归类为 ASD (n= 109) 或非 ASD (n= 160) 的非典型发育幼儿使用 aUtlsm 特征筛查 - 第 2 部分 {BISCUIT-第 2 部分) 进行了研究。参与者分为四个年龄组:12-18个月、19-24个月、25-31个月和32-39个月。使用析因多元方差分析来评估 BISCUIT-Part 2 结构域上的年龄和诊断组差异。出现了一个总体趋势,即患有 ASD 的幼儿似乎比非典型发育的非 ASD 幼儿有更严重的症状,并且随着年龄的增长,合并症行为呈增加趋势。讨论了结果和影响。

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