NA;Between 1985 and 1990, 340 eyes with rhegmatogenous retinal detachment lpar;RRDrpar; and severe lpar;stage C3 or worserpar; proliferative vitreoretinopathy lpar;PVRrpar; were treated with vitrectomy and randomly selected to receive perfluoropropane gas or silicone oilsemi; 183 eyes had undergone no prior vitrectomy lpar;group 1rpar;, and 157 eyes had undergone prior vitrectomy with intraocular gas tamponade lpar;group 2rpar;. No differences were found between eyes in the two groups in achieving visual acuity of 5sol;200 or better lpar;44percnt; vs. 39percnt;rpar;, macular reattachment lpar;78percnt; vs. 77percnt;rpar;, or complete retinal reattachment lpar;67percnt; for both groupsrpar;. In group 1, 74 eyes achieved complete retinal reattachment after only one operationsemi; 41 additional eyes achieved reattachment after a second surgical procedure. In group 2, these numbers were 74 and 26, respectively. Eyes treated successfully after more than one operation were less likely to regain a visual acuity of 5sol;200 or better than those successfully treated with one operation lpar;P 0.01rpar;. There was no difference in hypotony between groups, but keratopathy was more frequent in eyes in group 2 lpar;P 0.05rpar;. The results suggest that differences in outcomes between group 1 and group 2 eyes are not as great as previously believed.
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