机译:优化人NK细胞生产:全自动分离,使用IL-21与自体饲养细胞改善体外扩增,以及产生抗CD123-CAR表达效应细胞
Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School, Hannover, Germany;
Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany;
Miltenyi Biotec GmbH, Bergisch Gladbach, Germany;
interleukin-3 receptor subunit alpha (CD123); acute myeloid leukemia; closed GMP-compliant Prodigy system; autologous feeder cells; chimeric antigen receptor-modified NK cells; IL-21;