Patients with primary hypercoagulopathies often present with recurrent, spontaneous deep venous thrombosis and pulmonary embolism. An adolescent eventually diagnosed with protein S deficiency presented with unilateral deep venous thrombosis documented ultrasonographically. Scintigraphic studies showed no evidence of pulmonary embolism but revealed a complete absence of and the abdoment. Subsequent ultrasonography and CT Radionuclide scintigraphy may play an important role in the serial evaluationof primary hypercoagulable states, particularly when pulmonary scintigraphy is combined with bilateral, lower extremity venography.
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