The development of asymmetric Michael additions for carbon-carbon bond formation is an important challenge in organic synthesis. These reactions have been performed under the influence of strong bases such as alkali metal alkoxides or hydroxides. Enantioselective Michael additions of organolithium, Grignard or diorganozinc derivatives are attractive ways to introduce chirality into organic compounds. The catalytic version of these reactions has been recently studied and described mostly with copper, nickel or cobalt salts as catalytic precursors. The double Michael reaction is also a synthetic strategy in organic synthesis which allows the construction of complex carbon frameworks through the formation of two bonds in one step.
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