首页> 外文期刊>pathology international >Epstein‐Barr virus genomes in Hodgkin's disease and non‐Hodgkin's lymphomas
【24h】

Epstein‐Barr virus genomes in Hodgkin's disease and non‐Hodgkin's lymphomas

机译:Epstein‐Barr virus genomes in Hodgkin's disease and non‐Hodgkin's lymphomas

获取原文
           

摘要

Seventeen of 40 cases of Hodgkin's disease (HD) and eight of 46 non‐Hodgkin's lymphomas (NHL) were associated with Epstein‐Barr virus (EBV) infection, judged by the EBER‐1in situhybridization (ISH) method. Approximately 40 incidence in HD was comparable to previous reports. Young children and elderly HD patients were more prone to be found EBV positive. Fourteen of 17 HD and two of 8 NHL cases with positive EBER‐1 ISH were also positive on LMP‐1 immunostaining. EBV might have a role in lymph‐omagenesis in these cases. The fact that 7 of 8 EBV‐related NHL were peripheral T cell lymphoma indicates the necessity of a larger‐scale survey on this subject. As the present study revealed four cases with positive LMP‐1 immunostaining but negative EBER‐1 ISH (1 HD, 3 NHL), LMP‐1 alone should not be regarded as a tool t

著录项

获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号