AIM: To determine the relation of echocardiographic subepicardial adipose tissue (SAT) thickness with anthropometric and clinical parameters in pubertal obese children. SUBJECTS AND METHODS: A total of 52 obese pubertal subjects (13.1+/-1.56 yr, 27 male patients) and 39 age- and gender-matched lean pubertal subjects (13.0+/-1.28 yr, 16 male patients) were included in the study. Serum glucose, lipid profile, and insulin levels were measured during the fasting state. Each subject underwent a transthoracic echocardiography and the SAT thickness was measured during end-diastole from the parasternal long-axis views. RESULTS: The obese pubertal subjects had significantly higher SAT, triceps skin fold (TSF) thickness (mm), waist (WC) and mid-arm circumference (MAC) values (cm) compared with lean pubertal subjects group (p0.05). As an optimal cut-off point, a SAT thickness of 5.25 mm determined IR with 92 sensitivity and 62.1 specificity. CONCLUSIONS: Our study showed that SAT thickness in obese pubertal children shows a good correlation with age, SDS-BMI, BMI, WC, MAC, TSF, and HOMA-IR. In addition, our results suggest that SAT thickness might be used as a supportive data for risk stratification of metabolic syndrome in obese children.
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机译：目的：确定青春期肥胖儿童超声心动图心外膜下脂肪组织 （SAT） 厚度与人体测量和临床参数的关系。受试者和方法： 该研究共纳入 52 名肥胖青春期受试者（13.1+/-1.56 岁，27 名男性患者）和 39 名年龄和性别匹配的瘦青春期受试者（13.0+/-1.28 岁，16 名男性患者）。在空腹状态下测量血清葡萄糖、血脂和胰岛素水平。每个受试者都接受了经胸超声心动图检查，并在舒张末期从胸骨旁长轴视图测量 SAT 厚度。结果：与瘦青春期受试者组相比，肥胖青春期受试者的SAT、肱三头肌皮肤褶皱（TSF）厚度（mm）、腰围（WC）和中臂围（MAC）值（cm）显著高于瘦青春期受试者组（p0.05）。作为最佳临界点，5.25 mm 的 SAT 厚度确定了 IR，灵敏度为 92%，特异性为 62.1%。结论：我们的研究表明，肥胖青春期儿童的SAT厚度与年龄、SDS-BMI、BMI、WC、MAC、TSF、HOMA-IR有良好的相关性。此外，我们的研究结果表明，SAT厚度可能被用作肥胖儿童代谢综合征风险分层的支持数据。
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