ABSTRACTA patient was reported with suspected acute post‐transfusion hepatitis C virus (HCV) infection, 5 months after the transfusion of 2 units of red cells. The archived serum samples of the two implicated donations were retested by the original 3rd‐generation assay together with another 3rd‐generation assay and RI‐BA III, and were tested for HCV RNA using the PCR. Both donations were anti‐HCV negative but one was found to be PCR positive. This donor was a regular donor and was identified as the husband of a donor identified 18 months earlier as being HCV positive. This case is an example of transmission of HCV in the window period of infection, and a probable example of the transmission of HCV from wife to husband through intimat
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