In our attempts at establishing a cancer cell line from various ascites of cancer bearing patients, a cell line was successfully established from the ascites of a 63‐year‐old female with primary ovarian tumor (embryonal carcinoma). Histological flndings of the peritoneum, due to metastasis, appeared to be cystadenocarcinoma, revealing the differentiation to non‐epitheual cells which formed coarse networks and fibers, and morphologic changes of tissue cultures also reflected such histologic findings. At present the subculture has reached the 95th population doubling level, and cultured cells have assumed the morphology of mesothelial cells or flbroblasts with about 50 chromosomes. As a human malignant cell line, it is useful for the study of human malignant tumor cell, ACTA PATH. JAP. 25: 89–9
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