How does a virus bore a hole in a cell?

摘要

Chemists in the US studying how viruses enter cells say their results could help in the search for new antiviral medicines. Stanford University chemists Richard Zare and Soonwoo Chah used cell and virus models to investigate an early stage in viral infection. Using lipid spheres called vesicles as cell mimics they studied the way the vesicles rupture after exposure to PEP1, a helix-shaped peptide that resembles a peptide found in the hepatitis C virus.