RATIONALE AND OBJECTIVESThe authors determine the utility of relative blood volume measurements (rBV) using a blood pool marker for magnetic resonance imaging (MRI) in detection of early testicular torsion.METHODSTesticular torsion was induced in rats by counterclockwise 720deg; rotation and fixation of the testis in the scrotum. MPEG-PL-DTPA-Gd enhanced MRI (30 micro;mol Gd/kg bolus injection) was performed 1 hour after torsion at 1.5 T using fat-suppressed three-dimensional fast spoiled gradient-recalled sequence for relative blood volume measurement and three-dimensional time-of-flight sequence for MR angiography (MRA).RESULTSThe rBV of the torqued testes was significantly lower (13.3 plusmn; 13.5) than that of testes with sham operation(97.7 plusmn; 5.3;PPCONCLUSIONSThe authors conclude that MPEG-PL-DTPA-Gd can be used to obtain functional (rBV), morphologic(tunica enhancement), and angiographic (venous engorgement, arterial compromise) findings that should improve the diagnosis of testicular torsion in the acute setting.
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