Background: From an evolutionary standpoint, olfaction is one of the oldest senses, and one that affects all aspects of life. This review discusses the influence of olfaction and pheromones on life. Methods: A literature search was conducted using MEDLINE (1966-2012), Embase (1988-2012), The Cochrane Library (1993-2013) and Ovid (1966-2012). Results: Olfaction plays an important role in life, from infancy through to adulthood and declining health in old age. Culture, memories and emotions, which add to life's complexity and overall enjoyment, are also influenced by olfaction. Conclusion: Olfaction has a chronological influence on life, affecting all aspects from the cradle to the grave; it plays a role in the quality of life as a key ingredient of human evolution, survival and enjoyment.
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