Intravascular Persistence of Hydroxyethyl Starch (HES) after Serial Granulocyte Collections Using HES in Man

摘要

Abstract.In 30 granulocyte donors undergoing one or more infusions of 6 hydroxyethyl starch (HES) solution plasma HES concentrations were measured by single radial immunodiffusion. Serial HES applications led to a cumulative increase in plasma HES levels. Up to 3 months after the last HES infusion, plasma concentrations in the range of 3 mg/ml were demonstrable. A possible influence of HES deposits upon reticuloendothelial system function is discussed.