Suppression of IgE Antibody Response against Ovalbumin by the Chemical Conjugate of Ovalbumin with a Polyaspartic Acid Derivative

摘要

Ovalbumin was modified with α,β-poly(2-hydroxyethyl)-DL-aspartamide which had been developed as a nontoxic plasma expander. Preadministration of the modified ovalbumin suppressed both primary and secondary antiovalbumin IgE response