LADA: A Type of Diabetes in its Own Right?

摘要

Latent Autoimmune Diabetes in the Adult, LADA has been investigated less than “classical”type 1 and type 2 diabetes and the criteria for and the relevance of a LADA diagnosis have beenchallenged. Despite the absence of a genetic background that is exclusive for LADA this form of diabetesdisplays phenotypic characteristics that distinguish it from other forms of diabetes. LADA isheterogeneous in terms of the impact of autoimmunity and lifestyle factors, something that posesproblems to therapy and follow-up, perhaps particularly in those with marginal positivity. Yet, thereappears to be clear clinical utility in classifying individuals as LADA.