A reduced-order model based on the coupled 1D-3D finite element simulations for an efficient analysis of hemodynamics problems

摘要

A reduced-order model for an efficient analysis of cardiovascular hemodynamics problems using multiscale approach is presented in this work. Starting from a patientspecific computational mesh obtained by medical imaging techniques, an analysis methodology based on a two-step automatic procedure is proposed. First a coupled 1D-3D Finite Element Simulation is performed and the results are used to adjust a reduced-order model of the 3D patientspecific area of interest. Then, this reduced-order model is coupled with the 1D model. In this way, three-dimensional effects are accounted for in the 1D model in a cost effective manner, allowing fast computation under different scenarios. The methodology proposed is validated using a patientspecific aortic coarctationmodel under rest and non-rest conditions.