Alpha-particle incidence in small targets

摘要

A method for the direct measurement of the frequency distribution of-particle incidence in targets of similar dimensions to cell nuclei is described. Inaddition to yielding the value of the mean dose in rads, these measurements enablethe variation of dose in small targets to be expressed as percentages of cell nucleireceiving zero, single or multiple incidences in a stated time interval. The relevanceof this ' particle incidence ' concept of dose is discussed in relation to carcinogenesisand illustrated by actual measurements in bones containing239Pu.