Tumour treatments see the light

摘要

DNA-seeking probes could deliver anticancer agents right to the heart of tumour cells, say chemists in Italy Nitric oxide (NO) is a promising anticancer agent, killing cancer cells mainly by reacting with their DNA, causing the strands to break. To deliver NO directly to DNA, Salvatore Sortino and Fiorella Callari from the University of Catania have combined a light-triggered NO donor with a DNA binding agent.