The fate of fragments of liver implanted in ectopic sites

摘要

AbstractImplanted fragments of liver in ectopic sites do not survive. The failure of survival is associated with lack of vascularization. This results in necrosis of coagulative type which later is replaced by connective tissue. An invasion of polymorphonuclear leukocytes can enhance the rate of this process. Regenerative stimuli such as partial hepatectomy do not change this sequence of events. The lack of vascularization of implants may be due to failure of eliciting an invasive vascular phenomenon which is seen in the implanted fragments of those tissues that survive in ectopic sites.