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高速コヒーレン卜ラマン分光

机译:高速相干拉曼光谱

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摘要

Coherent Raman scattering is a nonlinear optical process that generates enhanced Raman signal by several orders of magnitude over spontaneous Raman scattering. The signal enhancement has made possible high-speed label- free biomedical imaging based on the vibrational signature of molecules. This short review introduces broadband, high-speed coherent Raman spectroscopy. Rapid-scan Fourier-transform coherent Raman spectroscopy and dual- comb coherent Raman spectroscopy have drastically shorten the acquisition time to take a broadband Raman spectrum. The high-speed and broadband coherent Raman spectroscopy promise significant improvements on the throughput of biomedical diagnosis such as large-area microscopy and flow cytometry.
机译:相干拉曼散射是一种非线性光学过程,它产生的拉曼信号比自发拉曼散射高出几个数量级。信号增强使得基于分子振动特征的高速无标记生物医学成像成为可能。这篇简短的综述介绍了宽带、高速相干拉曼光谱。快速扫描傅里叶变换相干拉曼光谱和双梳相干拉曼光谱大大缩短了获取宽带拉曼光谱的时间。高速和宽带相干拉曼光谱有望显著提高生物医学诊断的通量,如大面积显微镜和流式细胞术。

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