Continuous monitoring of micturition pattern in nonhuman primates: Similarities to humans

摘要

AbstractMost experimental urodynamic studies have been carried out in animals under anesthesia. This study is performed on awake, unrestrained, upright animal models phylogenetically similar to humans. Five female rhesus monkeys were monitored for their micturition pattern using the system described in Part I. The voiding frequency, physiologic diuresis, and the early voiding correspond well to those of humans. A peak flow nomogram was constructed based on 357 urinations. It depicts a non‐linear relation of peak flow to increasing voided volume. The nomogram is similar in pattern to those developed for humans.These findings suggest that the rhesus monkey is one of the best animal models to study the function of lower urinary tract. © 1992 Wiley‐Liss,