Physical inactivity is a risk factor for stroke. This population-based cohort study investigates the risk for subclinical brain infarction and chronic white matter changes measured by MRI in individuals that perform different levels of activity on a regular basis. The study finds the risk for infarction, but not for white matter changes, to be significantly reduced in active subjects independent of classical risk factors. Activity, however, needs to be vigorous to be effective. The study supports the role of inactivity as an independent cerebrovascular risk factor. Physicians and healthcare providers should encourage their elderly patients to remain physically active.
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