Multimodality Exploration of Event‐Related Potentials in Chronic Alcoholics

摘要

Short‐ and long‐latency auditory evoked potentials (SAEPs and LAEPs), visual‐evoked potentials (VEPs), and contingent negative variation (CNV) were studied in 32 chronic alcoholics and their age‐, sex‐, and education‐matched control subjects. The alcoholics exhibited a delayed SAEP peak V and an increase in the III‐V and I‐V intervals, increased VEP P100 latency, increased LAEP N2 and P3 latencies and increased LAEP N1‐P2 amplitude. The analysis of the anomalies at a clinical level indicates a differential sensitivity of the event‐related potentials. The parameters most sensitive to chronic alcohol consumption were (in descending order) P3 latency, peak V latency, the I‐V and III‐V inte