The frequency and the possible age-related characteristics of gastro-oesphageal reflux disease (CORD) were investigated in 195 consecutive elderly subjects (mean age 74 years), referred to endoscopy for abdominal symptoms or sideropenic anaemia. In the 105 of these patients in whom there was any suspicion of GORD, 24-hour pH monitoring was carried out. All the patients were interviewed before the examinations.Erosive or complicated (grade 2–4) oesophagitis was found in 18of patients. The main symptoms in these patients were dysphagia, respiratory symptoms and vomiting. Chronic cough, hoarseness or wheezing were present in 57of patients with oesophagitis compared with 33of those without oesophagitis (p<0.001). The occurrence of heartburn and regurgitation did not differ significantly between patients with or without oesophagitis, although the mean symptom scores were higher in those with oesophagitis. Dvspepsia and chest pain were not typical symptoms in oesophagitis. Of patients with oesophagitis 29had no typical symptoms of GORD; only 24of patients with regurgitation had oesophagitis. In 24-hour pH monitoring, a significant increase in the occurrence of symptoms was not seen until total reflux time pH<4 exceeded 10. The occurrence of heartburn did not correlate with the extent of reflux in the pH study. In conclusion, typical symptoms of GORD in the aged were regurgitation, dysphagia, respiratory symptoms and vomiting rather than heartbur
展开▼
