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Antibiotic Efficacy and Characterization of Mangrove Metabolites against UTI Microbes

机译:红树林代谢物对尿路感染微生物的抗生素疗效和表征

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摘要

In vitro antibacterial aptitude of Avicennia marina, A. marina var acutissima, Rhizophora mucronata, and R. annamalayana leaves were evaluated for urinary tract infective bacterial strains. A. marina var. acutissima and R. annamalayana methanolic extracts had diverse phytochemicals and demonstrated lower antibacterial activity at the concentrations of 100 to 250 ig.mLT1 and greater activity at 500 to 1,000 ig.mL~1. The minimum inhibitory concentration and minimum bactericidal concentration intensity of methanolic extracts were at 150 to 375 ig.mlr1. Alkaloids and genstine were noted in TLC fractionation, and their bioactivities were determined in bioautography analysis. Active functional groups OH alcoholic (hydrogen bond), C-H methylene, and C-O- aldehyde were present in both active guided fractions, but R_2C=CH_2 alkene and N-O nitraso groups were only in A. marina var. acutissima.
机译:评估了 Avicennia marina、A. marina var acutissima、Rhizophora mucronata 和 R. annamalayana 叶的体外抗菌能力,以检测尿路感染性细菌菌株。A. marina var. acutissima 和 R. annamalayana 甲醇提取物具有多种植物化学物质,在 100 至 250 [ig.mLT1 浓度下表现出较低的抗菌活性,在 500 至 1,000 ig.mL~1 时表现出更高的活性。甲醇提取物的最小抑菌浓度和最小杀菌浓度强度为150-375 ig.mlr1。在TLC分馏中观察到生物碱和genstine,并在生物自学分析中测定其生物活性。活性诱导组分中均存在活性官能团OH醇(氢键)、C-H亚甲基和C-O-醛,但R_2C=CH_2烯烃和N-O硝基团仅存在于A. marina var. acutissima中。

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