Adverse effects of drugs used to treat hyperlipidaemia

摘要

The different-drugs used to treat hyperlipidaemia have characteristic adverse effects.Bile acid sequestrantsmdash;gastrointestinal upsets, acidosis, malabsorption of vitamins and other drugs.HMG CoA reductase inhibitorsmdash;myositis and abnormalities of liver function tests, interactions with fibric add derivatives.Fibric acid derivativesmdash;gastrointestinal upsets, myositis, abnormalities of liver function tests, cholelithiasis, photosensitivity, interactions with warfarin, interactions with HMG CoA reductase inhibitors, deterioration in renal function.Probucolmdash;diarrhoea, prolongation of the QTc interval in the electrocardiogram.Nicotinic add derivativesmdash;skin flushing, gastrointestinal upsets, hepatitis, hyperglycaemia and hyperuricaemia.Fish oilsmdash;epistaxis, interaction with anticoagulants, hyperglycaemia.