The late psychosocial complications in patients with posterior fossa tumor (Medulloblastoma)

摘要

Primary brain and other central nervous system (CNS) tumors are the most common solid tumors that occur during childhood, with an annual US rate of approximately 3.0 cases per 100,000 persons aged 19 years or younger.Treatment of posterior fossa tumors has been associated with improved survival rates, but this increased survival has come with a price. Morbidity is high among survivors, both from consequences of the primary lesion and from the effects of the multimodal treatment on the developing brain. Surgery, radiation, and chemotherapeutic agents may produce both immediate and radiation) in addition to academic and behavioral changes.However, children treated with surgery and chemotherapy may not exhibit the same significant neuropsychiatric compromise.