As of December 31, 2017, a total of 9,242 liver transplants have been performed in 67 institutions in Japan. There were 447 deceased-donor transplants (444 from heart-beating donors and 3 from non-heart-beating donors) and 8,795 living-donor transplants. The annual total of liver transplants in 2017 was 416 (69 deceased-donor transplants and 347 living-donor transplants). The most frequent indication was cholestatic disease, followed by neoplastic disease and hepatocellular disease. As for hepatocellular disease in 2017, cirrhosis due to hepatitis C and B decreased (13 and 8, respectively), whereas alcoholic cirrhosis markedly increased (32). Patient survival following transplantation from heart-beating donors (444 transplants: 1-year 89.1, 3-year 85.2, 5-year 82.9, 10-year 75.4, 15-year 70.7) was similar to that from living-donors (8,794 transplants: 1-year 85.0, 3-year 80.9, 5-year 78.5, 10-year 73.2, 15-year 68.5, 20-year 65.7, 25-year 64.6). Graft survival was very much the same as patient survival (heart-beating donors: 1-year 88.4, 3-year 84.5, 5-year 82.2, 10-year 74.7, 15-year 70.1，living-donors: 1-year 84.3, 3-year 79.9, 5-year 77.3, 10-year 71.4, 15-year 66.3, 20-year 63.3, 25-year 61.9). Survival data are reported according to age and sex of recipient, indication, age and sex of donor, ABO-compatibility, and other factors.
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