An immune response gene linked to MHC in man

摘要

With a view to finding a relationship between immune response and MHC in man, 83 D negative mothers with allo‐into‐D antibodies and 26 PLA1negative mothers with allo‐anti‐PLA1antibodies were investigated as regards their HLA‐A, B and DR antigens. We have found that there is a highly significant relation between the DR3 antigen and an immune response to the PLA1antigen, but none to the