Crouch and Wilson demonstrated a strong correlation between carcinogenic potencies in rats and mice, supporting the extrapolation from mouse to man. Bernsteinet al., however, show that the observed correlation is mainly a statistical artifact of bioassay design. Crouchet al.have a comeback. This paper will review the arguments and present some new data. The correlation is largely (but not totally) tautological, confirming results in Bernsteinet al.
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机译：Crouch 和 Wilson 证明了大鼠和小鼠的致癌效力之间存在很强的相关性，支持了从小鼠到人类的推断。 然而，Bernsteinet 等人表明，观察到的相关性主要是生物测定设计的统计伪影。Crouchet al.卷土重来。本文将回顾这些论点并提出一些新数据。这种相关性在很大程度上（但不是完全）是同义的，证实了Bernsteinet al.的结果。
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