Interventional Atrioseptostomy by Application of Monopolar High-Frequency Alternating CurrentIn Vitro Evaluation of a New Device

摘要

RATIONALE AND OBJECTIVESThe authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria.METHODSThe device consists of a symmetrical cage of six superelastic monofile wires, including a microthermistor that is placed via a catheter into a punctured hole in the porcine foramen ovale. The device is used as a differential electrode for monopolar, temperature-controlled application of high-frequency alternating current for thermal modelling of ASD.RESULTSApplication of current for 60 seconds caused temperature-dependent, sized ASDs.CONCLUSIONIn vivo animal studies to evaluate possible side effects and long term patency of the ASDs are justified and warranted.