Substrate screening made simple

摘要

A simple assay for identifying protease substrates will make such experiments accessible to everyone,say scientists in Switzerland.Proteases are enzymes that hydrolyse peptide bonds,and are involved in many important processes in the body.Identifying protease substrates is important for studying the structure and function of these enzymes,and can also produce leads for drug development,explained Jean-Louis Reymond,a bioorganic chemist from the University of Bern.