Further Studies with the Potentiated Reagin Response to Egg Albumin

摘要

High titers of reagins were obtained in rats by initial immunization with egg albumin and B. pertussis and subsequent infection with larvae of N. brasiliensis. These antibodies have physicochemical properties and biological activities identical to those of rat immunoglobulin E (IgE). IgE type antibodies against N. brasiliensis are also produced in these same animals but not until the titers of IgE against egg albumin have decreased.