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Vaccination against human papillomavirus types 16 and 18: the impact on cervical cancer.

机译:接种 16 型和 18 型人瘤病毒疫苗:对宫颈癌的影响。

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摘要

Throughout the 20th Century, vaccines have proven successful in lengthening life expectations in different regions of the world. Since cervical cancer has become recognized as a potential complication of a genital infection, the prospect of vaccination offers new hope for global cervical cancer control.Cervical cancer is the second most common cancer among women worldwide, with an annual incidence of approximately half a million cases. Over 80 of these occur in developing countries, where case fatality rates are disproportionately higher than in developed regions i. An important reason for the relatively low cancer incidence in developed countries is that many of them have implemented cervical cancer prevention by means of programmed cytological screening. This has greatly reduced the cervical cancer incidence and mortality over recent decades 2.
机译:在整个20世纪,疫苗已被证明可以成功地延长世界不同地区的预期寿命。由于宫颈癌已被公认为生殖器感染的潜在并发症,疫苗接种的前景为全球宫颈癌控制提供了新的希望。宫颈癌是全球女性第二大常见癌症,年发病率约为五十万例。其中80%以上发生在发展中国家,其病死率高得不成比例地高于发达地区[i]。发达国家癌症发病率相对较低的一个重要原因是,许多发达国家已经通过程序化细胞学筛查实施了宫颈癌预防。近几十年来,这大大降低了宫颈癌的发病率和死亡率[2]。

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